Bee venom phospholipase A2 (PLA) represents the major allergen and antigen in allergic and non-allergic individuals sensitized to bee sting. We have studied specific activation of peripheral T cells by different structural and conformational variants of PLA and secretion of cytokines regulating IgE
β¦ LIBER β¦
Immunologic Investigations of T-Cell Regulation of Human IgE Antibody Secretion and Allergic Responses
β Scribed by David M. Essayan; Guha Krishnaswamy; Shau-Ku Huang
- Book ID
- 115638818
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 323 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1046-2023
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## Abstract Suppression of the antibody response by supraoptimal numbers of T helper cells was studied __in vitro__ and found to have both a specific and a nonspecific component. Suppression did not depend on direct cell contract of T and B cells, as supernatants of activated T cells were just as i