Immunologic characterization of chronic lymphocytic leukemia cells
β Scribed by Theresa L. Whiteside; Alan Winkelstein; Bruce S. Rabin
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 844 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0008-543X
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B cell and T cell characteristics of circulating lymphocytes were studied in 13 patients with chronic lymphocytic leukemia (C.L.L.). Immunofluorescence of surface immunoglobulins and rosette formation using sensitized sheep red blood cells were employed to detect B cells. Rosette formation with untr
The humoral antibody immunodeficiency in two patients with T-cell chronic lymphocytic leukemia (T-CLL) appeared to be the result of immunoregulatory abnormalities in the leukemic T-cell populations. Both patients had CD4-t CD45RS "virgin" or suppressor-inducer T-CLL, but Patient 1 had hypogammaglobu