Immunologic and steroid binding properties of the GCDFP-24 protein isolated from human breast gross cystic disease fluid

Mitogenic effect of the 15-kDa gross cys

Mitogenic effect of the 15-kDa gross cystic disease fluid protein (GCDFP-15) on breast-cancer cell lines and on immortal mammary cells

✍ Paola Cassoni; Anna Sapino; Darrow E. Haagensen; Carlo Naldoni; Gianni Bussolati 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 540 KB

## Abstract The biological significance of a major protein component in the fluid of gross cystic breast disease and a recognized marker of apocrine metaplasia, __i.e.__ the 15‐kDa glycoprotein (GCDFP‐15), is presently unknown. We have added GCDFP‐15 to cell culture medium and tested its effect on