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Immunolocalization of metallothionein (MT), and X.R.M.A. localization of zinc in hamster skin.

✍ Scribed by A.John Morgan; Carole Winters


Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
384 KB
Volume
17
Category
Article
ISSN
1065-6995

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The transient nuclear localization of metallothionein during cell growth and differentiation may be related to the increased requirement of zinc for DNA synthesis, activation of metalloenzymes, and transcription factors. Treatment of 3T3-L1 fibroblasts with aphidicolin, an inhibitor of nuclear DNA s