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Immunohistochemical study of cytochrome P450 2C and 3A in human non-neoplastic and neoplastic tissues

✍ Scribed by T. Yokose; Mikio Doy; Tomoyoshi Taniguchi; Tsutomu Shimada; Motoharu Kakiki; Tohru Horie; Yasushi Matsuzaki; Kiyoshi Mukai

Book ID
118297406
Publisher
Springer
Year
1999
Tongue
English
Weight
901 KB
Volume
434
Category
Article
ISSN
1432-2307

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Cytochrome P450 (CYP) 2A5 is involved in the metabolism of carcinogens like aflatoxin B1 and N-nitrosodiethylamine (NDEA), and CYP2A5 levels are increased in some pathological states of the liver (e.g., infectious hepatitis and porphyria). We analyzed the expression of CYP2A5 during experimental liv