New hypotheses about the structure–funct
✍
Robert A. Pearlstein; Qi-Ying Hu; Jing Zhou; David Yowe; Julian Levell; Bethany
📂
Article
📅
2010
🏛
John Wiley and Sons
🌐
English
⚖ 681 KB
## Abstract LDL cholesterol (LDL‐C) is cleared from plasma via cellular uptake and internalization processes that are largely mediated by the low‐density lipoprotein cholesterol receptor (LDL‐R). LDL‐R is targeted for lysosomal degradation by association with proprotein convertase subtilisin‐kexin