Immunohistochemical localization of membrane type 1-matrix metalloproteinase (MT1-MMP) in osteoclasts in vivo
β Scribed by K. Irie; ; E. Tsuruga; ; Y. Sakakura; ; T. Muto; ; T. Yajima
- Book ID
- 117841589
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 490 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0040-8166
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## Abstract Matrix metalloproteinases (MMPs) are multidomain zincβdependent proteolytic enzymes that play pivotal roles in many normal and pathological processes. Some members of the MMP family are anchored to the plasma membrane via specialized domains and thus are perfectly suited for pericellula
## Abstract An advanced glycation end products (AGE)/a receptor for AGE (RAGE) axis plays a key role in diabetic vascular complications. Membrane type 1βmatrix metalloproteinase (MT1βMMP) has been shown to function not only as a proteolytic enzyme but also as a signaling molecule. In this study, we