Hepatocyte growth factor is a protein growth factor with a strong mitogenic effect on hepatocytes. Recently, hepatocyte growth factor and hepatocyte growth factor messenger RNA have been extracted from several organs of humans, rats and rabbits. This study was undertaken to comprehensively define an
Immunohistochemical Localization of Hepatocyte Growth Factor Protein in Pancreas Islet A-Cells of Man and Rats
β Scribed by Tsuda, Hiroyuki ;Iwase, Teruhiko ;Matsumoto, Kazuyuki ;Ito, Mitsuya ;Hirono, Iwao ;Nishida, Yoshihisa ;Yamamoto, Masami ;Tatematsu, Masae ;Matsumoto, Kunio ;Nakamura, Toshikazu
- Book ID
- 108579593
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1992
- Tongue
- English
- Weight
- 503 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0910-5050
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Recently, the existence of the large latent transforming growth factor β€ (TGF-β€) complex, consisting of TGF-β€, the N-terminal part of its precursor (latency-associated peptide [LAP]), and the latent TGF-β€ binding protein (LTBP), was demonstrated in rat liver parenchymal cells (PC) and stellate cells
nases. These results suggest that PTK, Ras, and PKC Hepatocyte growth factor (HGF) stimulated mitogenplay roles in MAP kinase activation induced by HGF and activated protein (MAP) kinases and MAP kinase kinase that MAP kinase activation resulting in AA release is in primary cultured rat hepatocytes.