Prostate glands of adult guinea pigs were stained for nerve growth factor (NGF) and epidermal growth factor (EGF) by immunohistochemical methods. Both NGF and EGF were localized diffusely in the cytoplasm of the glandular epithelial cells, and also in their secretory products. These findings suggest
Immunohistochemical localization of cyclic nucleotides in guinea pig lip
β Scribed by Yoshiki Miyachi; Sadao Imamura; Chikako Tanaka; Takayoshi Kuno; Nobuyoshi Yoshida
- Publisher
- Springer-Verlag
- Year
- 1980
- Tongue
- English
- Weight
- 987 KB
- Volume
- 269
- Category
- Article
- ISSN
- 0340-3696
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β¦ Synopsis
The cellular localization of cAMP and cGMP in the guinea pig lip was investigated with an indirect immunofluorescence technique, cAMP was distributed both in cell membranes and cytoplasmic elements with coarse and granular intranuclear fluorescence, while cGMP was localized in nuclear sites including nuclear membranes as well as cell membranes and cytoplasm. In the basal portion, both cAMP and cGMP fluorescence was weaker in cytoplasm and cell membranes than seen in the upper portion.
π SIMILAR VOLUMES
Plasma levels of cyclic AMP and cyclic GMP were determined in 35 guinea pigs for up to 9 days following subcutaneous passage of L2C leukemia cells. Twenty guinea pigs into which normal syngeneic guinea pig thymocytes were passaged served as controls. Cyclic AMP levels in plasma showed little change