Immunohistochemical localisation of two phosphatidylinositol 4-kinase isoforms, PI4K230 and PI4K92, in the central nervous system of rats

Immunohistochemical localization of phos

Immunohistochemical localization of phosphorylated protein kinase R and phosphorylated eukaryotic initiation factor-2α in the central nervous system of SJL mice with experimental allergic encephalomyelitis

✍ Anuradha Chakrabarty; Marsha M. Danley; Steven M. LeVine 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 773 KB

## Abstract Inflammatory cells enter the CNS and target myelin in multiple sclerosis (MS) and experimental allergic encephalomyelitis (EAE), a model of MS, and inflammation is thought to induce stress responses in the CNS. Protein kinase R (PKR) and eukaryotic initiation factor‐2α (eIF2α) undergo p