Immunohistochemical expression of Rho GTPases in ameloblastomas
✍ Scribed by Filipe Modolo; Michelle Tillmann Biz; Suzana Machado de Sousa; Rodolfo de Lima Fachinelli; Virgínia Oliveira Crema
- Book ID
- 111255567
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 741 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0904-2512
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Small GTPases of the Rho family are involved in the regulation of a variety of cellular processes, such as the organization of the microfilamental network, cell-cell contact and malignant transformation. To address the question of whether Rho proteins are involved in carcinogenesis in man, we compar
## Abstract Rho proteins belong to the small GTPases superfamily. They function as molecular switches that, in response to diverse stimuli, control key signaling and structural aspects of the cell. Although early studies proposed a role for Rho GTPases in cellular transformation, this effect was un