Immunohistochemical evaluation of squamous cell carcinoma antigen and s-100 protein-positive cells in human malignant esophageal tissues

A c-rasHa mutation in the metastasis of

A c-rasHa mutation in the metastasis of a human papillomavirus (HPV)-18 positive penile squamous cell carcinoma suggests a cooperative effect between HPV-18 and c-rasHa activation in malignant progression

✍ Paula F. Leis; Kristin R. Stevens; Susan C. Baer; Dov Kadmon; Leonard H. Goldber 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 381 KB 👁 1 views

## BACKGROUND. Human papillomaviruses (HPV) have been implicated in the etiology of anogenital squamous epithelial tumors. Of the 65 HPV strains, subtypes HPV-16 and HPV-18 frequently are associated with malignant conditions and are capable of transforming keratinocytes in vitro. However, addition