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Immunohistochemical evaluation of lymph node micrometastases from gastric carcinomas

✍ Scribed by Kimitaka Ishida; Tsutomu Katsuyama; Atsushi Sugiyama; Seiji Kawasaki

Book ID
102649133
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
690 KB
Volume
79
Category
Article
ISSN
0008-543X

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✦ Synopsis

RESULTS.

Metastases were confirmed in 230 lymph nodes (9.4%) stained with H & E, moto, Japan. and an additional 201 lymph nodes (17.6%) had micrometastases identified only by immunostaining for cytokeratin (197 lymph nodes) and/or CEA (66). Carcinomas with micrometastases had significantly worse prognoses at Stage II. Between the two histologic types of gastric carcinoma, the diffuse type had more micrometastases than the intestinal type.

CONCLUSIONS.

The findings of this study indicate that the presence of micrometastases in lymph nodes is an indispensable factor in determining the prognosis of gastric carcinoma patients.

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