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Immunohistochemical Detection of Pulmonary Cytochrome P450IA and Metabolic Activities Associated with P450IA1 and P450IA2 Isozymes in Lung Cancer Patients

✍ Scribed by Sisko Anttila, Harri Vainio, Eino Hietanen, Anne-Marie Camus, Christian Malaveille, Gisele Brun, Kirsti Husgafvel-Pursiainen, Lasse Heikkilä, Antti Karjalainen and Helmut Bartsch

Book ID
124295580
Publisher
Environmental Health Information Service
Year
1992
Tongue
English
Weight
548 KB
Volume
98
Category
Article
ISSN
0091-6765

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Smoking and peripheral type of cancer ar
Smoking and peripheral type of cancer are related to high levels of pulmonary cytochrome P450IA in lung cancer patients
✍ Sisko Anttila; Eino Hietanen; Hard Vainio; Anne-Marie Camus; Harry V. Gelboin; S 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 669 KB

## Abstract A specific member of the cytochrome P450 super‐family of enzymes, designated P450IA (including 2 isozymes, P450IAI and P450IA2), which is involved in the metabolic activation of polycyciic aromatic hydrocarbons and aromatic amines, was studied in lung tissue from 25 lung cancer patients