Immunohistochemical detection of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 expression in breast carcinomas : Comparison on cell block, needle-core, and tissue block preparations

Evaluation of new monoclonal antibodies

Evaluation of new monoclonal antibodies in detection of estrogen receptor, progesterone receptor, and Her2 protein expression in breast carcinoma cell block sections using conventional microscopy and quantitative image analysis

✍ K. Z. Hanley; M. T. Siddiqui; D. Lawson; C. Cohen; A. Nassar 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 372 KB 👁 1 views

## Abstract Accurate assessment of estrogen receptor (ER), progesterone receptor (PR), and Her2 status of breast carcinomas is critical for predicting response to systemic therapies. Recently, developed rabbit monoclonal antibodies (RMab) are reported to have higher sensitivity than murine monoclon