Immunohistochemical analysis of ras p21 expression in normal, pre-malignant and malignant oral mucosa
β Scribed by S. Kannan; Prabha Balaram; M. Radhakrishna Pillai; G. Jagadeesh Chandran; M. Krishnan Nair
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- French
- Weight
- 436 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Multidrug resistance (MDR) in human cancer is often associated with over-expression of the mdr-1 gene, which encodes a 170-kDa transmembrane protein, termed P-glycoprotein (P-gp). We evaluated the immunoreactivity of P-gp in oral tissues at different stages of tumorigenesis in the Indian population
Recent reports of p53 positivity in the normal mucosa of some head and neck cancer patients have been taken as evidence for field cancerization and hence a likelihood of the development of further tumours, yet few papers report the clinical significance of this finding through long-term follow-up. T
## Abstract ## BACKGROUND The Eβcadherinβmediated cell adhesion system is frequently inactivated by multiple mechanisms and is involved in tumor progression in many types of cancer. Recently, the authors reported a novel cell membrane glycoprotein, dysadherin, which has an antiβcellβcell adhesion
Epithelial dysplasia is usually used to establish the prognosis of oral premalignant lesions. Its assessment, however, is subjective and does not always correctly predict the outcome of the lesions in terms of malignant transformation. Early molecular alteration(s) that dictate the development of ca