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Immunohistochemical analysis of Bcl-2 and Bax oncoproteins in rabbit craniomandibular joint

✍ Scribed by Qin Huang; Baldev Singh; Mohamed Sharawy

Book ID
113465465
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
540 KB
Volume
49
Category
Article
ISSN
0003-9969

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Bcl-2 is a proto-oncogene which is involved in prolonging cell survival by inhibiting programmed cell death. Bax and bcl-x are members of the bcl-2 family; when overexpressed, they can counteract the ability of bcl-2 to inhibit apoptosis. This suggests a model in which the ratios of bcl-2 to bax and