Immunoglobulins inhibit pathophysiological effects of anti-GQ1b-positive sera at motor nerve terminals through inhibition of antibody binding

Concanavalin a inhibits pathophysiologic

Concanavalin a inhibits pathophysiological effects of anti-ganglioside GQ1b antibodies at the mouse neuromuscular synapse

✍ Roland W. M. Bullens; Susan K. Halstead; Graham M. O'Hanlon; Jean Veitch; Peter 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 440 KB

## Abstract Anti‐GQ1b antibodies are present in the Miller Fisher syndrome (MFS), a monophasic neuropathy characterized by ataxia, areflexia, ophthalmoplegia, and sometimes cranial muscle weakness. We have previously shown, at the mouse neuromuscular junction (NMJ) ex vivo, that anti‐GQ1b antibodie