𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Immunoglobulin deposits in skin in systemic lupus erythematosus

✍ Scribed by M. O. Wierzchowiecki; F. P. Quismorio; G. J. Friou

Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
907 KB
Volume
18
Category
Article
ISSN
0004-3591

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✦ Synopsis

Abstract

Immunoglobulin deposits in the dermal‐epidermal junction of clinically normal skin from patients with SLE were eluted by acid buffer. The eluates contained antinuclear and antibasement membrane antibody activities. The anti‐BM antibody reacted with skin and esophageal but not glomerular basement membrane. Enzymatic studies indicated that the antibody reacted with carbohydrate moeities in the basement membrane. The anti‐BM antibody was not present in corresponding sera of SLE patients.

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