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Immunoglobulin A against viral capsid antigen of Epstein-Barr virus and indirect mirror examination of the nasopharynx in the detection of asymptomatic nasopharyngeal carcinoma

✍ Scribed by Zong Yong-Sheng; Jonathan S. T. Sham; M. H. Ng; Ou Xing-Tai; Guo Yuan-Qing; Zheng Shou-Ang; Liang Jin-Sheng; Qiu Hong

Publisher: John Wiley and Sons
Year: 1992
Tongue: English
Weight: 487 KB
Volume: 69
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19920101)69:1<3::aid-cncr2820690104>3.0.co;2-7

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The Epstein-Barr virus (EBV) open reading frame BHRF1, a homologue of the oncogene bcl-2, was cloned from a patient with nasopharyngeal carcinoma (NPC) and overexpressed in Escherichia coli. The resulting recombinant BHRF1 fusion protein, with an apparent molecular weight of 35 KD, was used as antig