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Immunogenicity of a hepatitis B DNA vaccine administered to chronic HBV carriers

✍ Scribed by Maryline Mancini - Bourgine; Héléne Fontaine; Christian Bréchot; Stanislas Pol; Marie-Louise Michel


Book ID
116958335
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
362 KB
Volume
24
Category
Article
ISSN
0264-410X

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Despite the availability of effective hepatitis B vaccines for many years, over 370 million people remain persistently infected with hepatitis B virus (HBV). Viral persistence is thought to be related to poor HBV-specific T-cell responses. A phase I clinical trial was performed in chronic HBV carrie