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Immunogenetics of multiple sclerosis and optic neuritis: DNA polymorphism of HLA class II genes

✍ Scribed by Niels Morling; Magnhild Sandberg-Wollheim; Lars Fugger; Jørgen Georgsen; Jens J. Hylding-Nielsen; Hans O. Madsen; Klaus Rieneck; Lars Ryder; Arne Svejgaard

Publisher
Springer-Verlag
Year
1992
Tongue
English
Weight
388 KB
Volume
35
Category
Article
ISSN
0093-7711

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✦ Synopsis

The human major histocompatibility complex (MHC), the HLA system, encodes at least three polymorphic series of class II transmembraneous glycoproteins designated DR, DQ, and DP. Each molecule consists of an a and a 13 glycoprotein chain (Kaufmann et al. 1984), each of which is coded by genes in the HLA-region. A great number of

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