Immunogenetic studies of juvenile dermatomyositis: hla-dr antigen frequencies
✍ Scribed by J. M. Friedman; L. M. Pachman; M. L. Maryjowski; R. M. Radvany; W. E. Crowe; V. Hanson; J. E. Levinson; C. H. Spencer
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 247 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0004-3591
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✦ Synopsis
Juvenile dermatomyositis (JDMS) is a chronic inflammatory disease of unknown etiology that occurs in children and is characterized by a typical rash and symmetric proximal myopathy often associated with soft tissue calcifications. We have previously reported a greater than expected frequency of HLA-B8 among 16 white patients with JDMS (1). In order to confirm this finding and to investigate its relationship to the pathogenesis of this rare disease, we undertook a multicenter collaborative investigation of immunoge-
From the Division of Clinical Genetics, Departments of Obstetrics and Gynecology and of Pediatrics and the Cecil H. and