Immunofluorescence study of patients with neuropathy and IgM M proteins
β Scribed by Masami Takatsu; Dr. Arthur P. Hays; Norman Latov; Gary M. Abrams; Raffaello Nemni; William H. Sherman; Eduardo Nobile-Orazio; Toyokazu Saito; Lorenza Freddo
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 967 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0364-5134
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Forty cases of polyneuropathy associated with IgM monoclonal gammopathy were retrospectively studied to investigate the relevance of clinical and electrophysiological features to M-protein antibody activity. There were 26 men and 14 women; mean age was 65 Β± 11.7 years at the time of the study. Thirt
## Abstract We studied the frequency and clinical correlates of different IgM specificities in 75 patients with neuropathy associated with IgM monoclonal gammopathy. Patients were tested for IgM reactivity with the myelinβassociated glycoprotein, PO, neurofilaments, and tubulin by immunoblot; with