Immunoexpression of cyclooxygenase-2 and p53 in oral squamous cell carcinoma
✍ Scribed by João Augusto Vianna Goulart Filho; Cassiano Francisco Weege Nonaka; Márcia Cristina da Costa Miguel; Roseana de Almeida Freitas; Hébel Cavalcanti Galvão
- Book ID
- 116214111
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 519 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1532-818X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Background: Immunoreactivity for p53 tumor supressor gene product is commonly found in human malignancies and some premalignant lesions, but its role in cancer development and its value as a marker of tumor biologic behavior is still unclear. Objectives: This study was undertaken to assess p53 immun
p53 is a tumour suppressor gene encoding a protein whose function is impaired in a very large proportion of human cancers. The objectives of this study were to determine the natural history of p53 alterations during stages of oral carcinogenesis, by comparing p53 immunoexpression in oral squamous ce