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Immunoelectron Microscopic Localization of Type 1 Plasminogen Activator Inhibitor in the Extracellular Matrix of Transforming Growth Factor-β-Activated Endothelial Cells

✍ Scribed by THOMAS J. PODOR; DAVID J. LOSKUTOFF

Book ID
119868063
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
471 KB
Volume
667
Category
Article
ISSN
0890-6564

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✍ Gouri Shanker; Dan Olson; Roger Bone; Rajinder Sawhney 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 372 KB

Transforming growth factor beta-1 (TGF-1 ), which is present in lung tissue, has been suggested to play a role in modulating vascular cell function in vivo. The action of TGF-1 in vivo, especially at the local site of application to connective tissue, is anabolic and leads to pulmonary fibrosis and