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IMMUNODOMINANCE IN MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I–RESTRICTED T LYMPHOCYTE RESPONSES 1

✍ Scribed by Yewdell, Jonathan W.; Bennink, Jack R.


Book ID
119944807
Publisher
Annual Reviews
Year
1999
Tongue
English
Weight
271 KB
Volume
17
Category
Article
ISSN
0732-0582

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This report shows that lymphoid tissues of mice which have resolved a primary infection with Leishmania major contain parasite-specific major histocompatibility complex (MHC) class I-restricted cytolytic CD8+ T cell precusors that can be expanded after specific restimulation in vitro with syngeneic