Immunodetection of human tumour-associated cell-bound antigens by human monoclonal antibodies
β Scribed by J.R.D. Tuson; D.A. Jacob; E.W. Pascoe; S.J.Y. Saxby
- Book ID
- 118901734
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 356 KB
- Volume
- 121
- Category
- Article
- ISSN
- 0022-1759
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## Abstract A panel of 3 monoclonal antibodies (MAbs) directed against human lung tumour cellβsurface antigens has been produced following immunizations with the established smallβcell lung cancer (SCLC) cell line, NClβH69, and with another SCLC cell line, CORβL32, recently derived from clinical ma
Five hybridomas producing human monoclonal antibodies (MAbs) of IgA and IgM isotypes reacting with the tumour associated TF antigen were generated after in vitro immunisation or antigen specific isolation of normal peripheral blood B cells using asialoglycophorin, a TF containing antigen. All 5 anti