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IMMUNODEFICIENCY IN FAMILIAL ERYTHROPHAGOCYTIC LYMPHOHISTIOCYTOSIS

✍ Scribed by Ammann, ArthurJ.; Addiego, J.; Ladisch, Stephan; Poplack, DavidG.; Blaese, R.Michael

Book ID
121968476
Publisher
The Lancet
Year
1978
Tongue
English
Weight
315 KB
Volume
312
Category
Article
ISSN
0140-6736

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A 21/2-month-old infant suffering from pyrexia, purpura, hepatosplenomegaly, pancytopenia and hyperlipidemia is reported. Liver and spleen biopsies revealed mononuclear histiocytic infiltration with marked erythrophagocytosis. The girl died at 7I/2 months of age. Her brother died in infancy with an