Immune mechanisms leading to abnormal B
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Valerie Roy; Gabriel Bonventi; Yongchun Cai; Ralph MacLeod; JoanβE. Wither
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Article
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2007
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John Wiley and Sons
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English
β 450 KB
## Abstract Polyclonal B cell activation is a hallmark of the immune dysregulation in New Zealand Black (NZB) mice. We have previously shown that the splenic B cell activation is associated with increased CD80 expression. Here we show that abnormal expansions of CD80βexpressing GC, CD5^+^, marginal