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Immunocytological localization of estrogen in human mammary carcinoma cells by horseradish—anti-horseradish peroxidase complex

✍ Scribed by Luna Ghosh; Dr. Bimal C. Ghosh; Tapas K. Das Gupta


Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
278 KB
Volume
10
Category
Article
ISSN
0022-4790

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✦ Synopsis


Tissues from 25 female and 2 male patients of mammary carcinoma were examined by the horseradish--anti-horseradish peroxidase complex to localize the presence of estrogen. Carcinoma cells of 10 females and 2 male patients showed positive staining by this technique. The nucleus and cytoplasmic membrane showed the reaction. This method is useful in identifying the exact location of the hormones or hormone-like substances in the malignant cells and, perhaps, will be of great help in selecting the patients for management.