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Immunocytochemical studies in the ceroid-lipofuscinoses (Batten disease) using antibodies to subunit c of mitochondrial ATP synthase

โœ Scribed by Westlake, Valerie J. ;Jolly, Robert D. ;Bayliss, Sheryl L. ;Palmer, David N.


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
717 KB
Volume
57
Category
Article
ISSN
0148-7299

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Ceroid lipofuscinosiiprotein (CLP), the major accumulating protein in several forms of ceroid lipofuscinosis, has an amino acid sequence that is identical to that of the Fo subunit c of normal bovine ATP synthase. Electrospray ionization mass spectrometry (ESI-MS) has shown that ovine CLP and normal