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Immunocytochemical localization of cytochrome P4501A1 in liver of rainbow trout (Oncorhynchus mykiss)

✍ Scribed by Susan M. Lester; Thomas A. Braunbeck; Swee J. Teh; John J. Stegeman; Michael R. Miller; David E. Hinton

Book ID: 119068355
Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 455 KB
Volume: 34
Category: Article
ISSN: 0141-1136
DOI: 10.1016/0141-1136(92)90094-3

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## Abstract The polycyclic aromatic hydrocarbons (PAHs) phenanthrene and retene (7‐isopropyl‐1‐methyl phenanthrene) are lethal to rainbow trout __(Oncorhynchus mykiss)__ larvae during chronic exposures. Phenanthrene is a low‐toxicity, non‐cytochrome P4501A (CYP1A)—inducing compound that accumulates