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Immunocytochemical Localization of 5α-Reductase in Rat Brain

✍ Scribed by Georges Pelletier; Van Luu-The; Fernand Labrie


Book ID
115546348
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
842 KB
Volume
5
Category
Article
ISSN
1044-7431

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## Abstract Testosterone (T) plays an important role in developing brain, dictating sex‐specific behavior and physiology. 3α,5α‐Reduced neurosteroids also regulate reproductive behavior. The key enzyme in the biosynthesis of these neurosteroids is 5α‐reductase (5α‐R), expressed as two isozymes, 5α‐