## Abstract BACH2 is a Bβcellβspecific transcription repressor and is also know as a tumor suppressor in B cell malignancy. Expression of BACH2 is induced in BCRβABL positive lymphoid cell lines including BV173 by imatinib, a molecular targeting agent for the treatment of chronic myeloid leukemia (
Immunocytochemical evaluation abl-Gene products in Leukemic Cell Lines
β Scribed by Sohei Kitazawa; Sakan Maeda; Taketoshi Sugiyama
- Book ID
- 112969729
- Publisher
- Springer US
- Year
- 1990
- Tongue
- English
- Weight
- 996 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1357-0560
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## Abstract Human lymphocytes have recently been described as an important physiological source of melatonin (__N__βacetylβ5βmethoxytryptamine), which could be involved in the regulation of the human immune system. On the other hand, stimulation of ILβ2 production by exogenous melatonin has been sh