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Immunocytochemical detection of p53 protein as an adjunct in cytologic diagnosis from pancreatic duct brushings in mucin-producing tumors of the pancreas

✍ Scribed by Iwao, Toshiyasu ;Tsuchida, Akira ;Hanada, Keiji ;Eguchi, Noriaki ;Kajiyama, Goro ;Shimamoto, Fumio

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 655 KB
Volume: 81
Category: Article
ISSN: 0008-543X
DOI: 10.1002/(sici)1097-0142(19970625)81:3<163::aid-cncr6>3.0.co;2-s

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✦ Synopsis

Hiroby endoscopic retrograde pancreatography (ERP). Specimens obtained by brushing shima University School of Medicine, Hirowere prepared on slides and subsequently fixed with ethanol. Papanicolaou stainshima, Japan.

ing and p53 immunocytochemistry were performed simultaneously. The ability of

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## BACKGROUND. It is often difficult to distinguish pancreatic carcinoma preoperatively from chronic pancreatitis. Therefore, we have developed a new method of detecting p53 immunoreactivity in cytologic material obtained by endoscopic retrograde pancreatic duct brushing (ERPDB). ## METHODS. Tw