Immunocompetence and spontaneous regression of metastatic renal cell carcinoma
β Scribed by Dr. Peter D. Boasberg; Frederick R. Eilber; Dr. Donald L. Morton
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 207 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Spontaneous remission of pulmonary metastases from renal cell carcinoma was correlated with a positive response to dinitrochlorobenzene (DNCB). When first seen, the patient was DNCB negative and a chest radiograph showed nodular densities in the right lung and left midlung. Six months after sensitization, the patient had a positive response to DNCB and no evidence of lung metastases. Three mo later, the patient developed brain metastases although Xβray examination showed no pulmonary nodules. A diminished response to DNCB was noted over the next several months and chest X ray verified the return of pulmonary metastases.
π SIMILAR VOLUMES
Ten publications between 1964 and 1971 suggest that tumor regression can be induced by hormone therapy in a limited number of patients with metastatic renal cancer. Subjective improvement occurs in about 50% of treated cases. Of 272 collected cases from the various reports (including a personal seri
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