Immunocharacterization of the mucin-type proteins from the intracellular stage of Trypanosoma cruzi
β Scribed by Vanina A. Campo; Carlos A. Buscaglia; Javier M. Di Noia; Alberto Carlos C. Frasch
- Book ID
- 108209953
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 449 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1286-4579
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## Abstract __Trypanosoma cruzi__ is the etiological agent of Chagas. Although the nuclear chromatin of this parasite is organized in the form of nucleosome filaments, its chromatin is physically and enzymatically fragile, and no condensation into chromosomes occurs during mitosis. All previous inv
+)-S-Ethyl- [3,7,11]-trimethyl-10,11-epoxy-2E,6E-dien-1-yl]-thiolcarbonate (1) and 4phenoxyphenoxy ethyl tetrahydropyranyl ether (2) were shown to be very active antireplicative agents against intracellular Trypanosoma cruzi amastigotes in in vitro assays. Both of them had previously presented high