Immunobiology of zinc and zinc therapy
✍ Scribed by Dirk Reinhold; Siegfried Ansorge; Kurt Grüngreiff
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 92 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0167-5699
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The standard therapy for preventing copper accumulation in Wilson's disease, D-penicillamine, has been a life-saving drug, but it has many side effects and some patients are completely intolerant. We have been using oral zinc as another approach to the therapy for Wilson's disease, with copper balan
After initial promotion of copper excretion with D-penicillamine, the effect of oral zinc sulphate (3 x 150 mg/day, loading dose; 3 x 100 mg/day, maintenance dose) in two children with clinically stable Wilson's disease was evaluated after completion of three years' treatment. The course, judged by