✦ LIBER ✦

Immunizations and infectious diseases in pediatric liver transplantation

✍ Scribed by Natasha Halasa; Michael Green

Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 123 KB
Volume: 14
Category: Article
ISSN: 1527-6465
DOI: 10.1002/lt.21605

No coin nor oath required. For personal study only.

✦ Synopsis

Liver transplantation (LTx) is an established and effective treatment for children with end-stage and metabolic liver disease. Improved surgical techniques and immunosuppressive regimens have led to enhanced short-term and long-term survival rates, which now approach or exceed 90%. Consequently, more children are being referred for LTx, and an increasing numbers of pediatric centers routinely perform this procedure. Infectious complications are an important cause of morbidity and mortality in children undergoing LTx. However, improvements in immune suppression management along with the availability of new antimicrobial agents and diagnostic tools have resulted in improved treatment and preventative regimens, thus reducing the impact of infectious complications on these children. This review provides an overview of the infectious complications and prevention strategies for children undergoing LTx.

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