Immunity to Transplanted Tumour: The Effect of Tumour Extracts on the Growth of Homologous Tumours in Rats
✍ Scribed by Baldwin, R W
- Book ID
- 109832728
- Publisher
- Nature Publishing Group
- Year
- 1955
- Tongue
- English
- Weight
- 710 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0007-0920
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## Abstract Inbred rats were treated with extranuclear tumour membrane fractions or 3 M KCl‐solubilized extracts of two antigenically distinct 3‐methylcholanthreneinduced sarcomas, Mc7 and Mc57. The rats developed tumour‐specific humoral antibody responses, but were not immune to tumour challenge.
## Abstract Natural killer (NK) cell activity was measured in a quantitative 6 h chromium release assay using sarcoma Mc7 cells as targets. The total NK lytic activity present in the spleen and blood of tumour‐bearing animals was compared with the corresponding values for age/sex/ parity‐matched an