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Immune response to Plasmodium vivax has a potential to reduce malaria severity

✍ Scribed by S. Chuangchaiya; K. Jangpatarapongsa; P. Chootong; J. Sirichaisinthop; J. Sattabongkot; K. Pattanapanyasat; K. Chotivanich; M. Troye-Blomberg; L. Cui; R. Udomsangpetch


Book ID
108701153
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
218 KB
Volume
160
Category
Article
ISSN
0009-9104

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Duffy antigen is the receptor used by Plasmodium vivax to invade erythrocytes. Consequently, individuals lacking Duffy antigen [Fy(-)] do not develop blood-stage infections. We hypothesized that naturally exposed Fy(-) humans may develop immune responses mainly to pre-erythrocytic stages and could b

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## Abstract We have investigated the immune response against the __Plasmodium falciparum__ gametocyte‐specific antigen Pf11‐1. This megadalton parasite molecule has been implicated in the process of erythrocyte rupture during gametogenesis. The molecule is composed in great part of degenerated nona