Immune response to Plasmodium vivax has a potential to reduce malaria severity
β Scribed by S. Chuangchaiya; K. Jangpatarapongsa; P. Chootong; J. Sirichaisinthop; J. Sattabongkot; K. Pattanapanyasat; K. Chotivanich; M. Troye-Blomberg; L. Cui; R. Udomsangpetch
- Book ID
- 108701153
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 218 KB
- Volume
- 160
- Category
- Article
- ISSN
- 0009-9104
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Duffy antigen is the receptor used by Plasmodium vivax to invade erythrocytes. Consequently, individuals lacking Duffy antigen [Fy(-)] do not develop blood-stage infections. We hypothesized that naturally exposed Fy(-) humans may develop immune responses mainly to pre-erythrocytic stages and could b
## Abstract We have investigated the immune response against the __Plasmodium falciparum__ gametocyteβspecific antigen Pf11β1. This megadalton parasite molecule has been implicated in the process of erythrocyte rupture during gametogenesis. The molecule is composed in great part of degenerated nona