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Immune protection against tuberculosis – When is immunotherapy preferable to vaccination?

✍ Scribed by J.M. Grange; L. Rosa Brunet; H.L. Rieder


Book ID
113938171
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
252 KB
Volume
91
Category
Article
ISSN
1472-9792

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## Abstract CD4^+^CD25^+^ natural T regulatory cells (Tregs) have been shown to suppress protective immune responses in several different vaccination models. Since the effect of Tregs on vaccination against tuberculosis (Tb) was unknown, we used a murine model to investigate whether natural Tregs s