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Immune Protection against HSV-2 in B-Cell-Deficient Mice

✍ Scribed by Kristen L. Dudley; Nigel Bourne; Gregg N. Milligan

Book ID
112272967
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
170 KB
Volume
270
Category
Article
ISSN
0042-6822

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## Abstract IL‐15 plays a crucial role in innate defense against viral infections. The role of IL‐15 in the generation and function of adaptive immunity, following mucosal immunization, against genital HSV‐2 has not been studied. Here, we report that immunized IL‐15^–/–^ mice were able to generate