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Immune privilege induced by regulatory T cells in transplantation tolerance

✍ Scribed by Stephen P. Cobbold; Elizabeth Adams; Luis Graca; Stephen Daley; Stephen Yates; Alison Paterson; Nathan J. Robertson; Kathleen F. Nolan; Paul J. Fairchild; Herman Waldmann


Book ID
110107282
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
543 KB
Volume
213
Category
Article
ISSN
0105-2896

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Immune privilege induced by regulatory T
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**Summary:** Immune privilege was originally believed to be associated with particular organs, such as the testes, brain, the anterior chamber of the eye, and the placenta, which need to be protected from any excessive inflammatory activity. It is now becoming clear, however, that immune privilege c

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There has been considerable recent progress in the characterization of the regulatory T cells that mediate tolerance in a number of transplantation models. The conditions that facilitate the generation of regulatory T cells point to the thymus, the nature of immune suppression and the dose of immuno