✦ LIBER ✦

Immune-mediated hemolytic anemia in children after liver and small bowel transplantation

✍ Scribed by Piotr Czubkowski; Mike Williams; Seema Bagia; Deirdre Kelly; Girish Gupte

Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 188 KB
Volume: 17
Category: Article
ISSN: 1527-6465
DOI: 10.1002/lt.22311

No coin nor oath required. For personal study only.

✦ Synopsis

Four children who underwent ABO-compatible combined liver and small bowel transplantation developed severe immunemediated hemolytic anemia. The main management strategies were early and aggressive treatment with steroids, the introduction of rituximab (an anti-CD20 monoclonal antibody), and the use of plasma exchange together with compatible but minimal blood transfusions. Three of the 4 children developed thrombi in the major vessels. In small bowel transplant patients, the early recognition of hemolytic anemia and intensified management with anticoagulation are necessary for the prevention of this complication.

📜 SIMILAR VOLUMES

Host immune suppression after small bowe

Host immune suppression after small bowel/liver transplantation in rats

✍ Xian-Chang Li; Robert Zhong; Gang He; Yoshiharu Sakai; Bertha Garcia; Anthony Je 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 511 KB

Small bowel bacterial overgrowth as a ca

Small bowel bacterial overgrowth as a cause of chronic diarrhea after liver transplantation in children

✍ Mack, David R. ;Dhawan, Anil ;Kaufman, Stuart S. ;Langnas, Alan N. ;Seemayer, Th 📂 Article 📅 1998 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 71 KB

Children who have undergone liver transplantation may develop chronic diarrhea for a number of reasons. Three children who underwent liver transplantation for liver failure, all of whom had had previous biliary and intestinal surgeries and whose postoperative course was marked by signs and symptoms