## Abstract ILโ17 can impact health in a variety of ways. It is protective for some pathogens but it is also associated with tissue damaging inflammation. By examining the role of ILโ17 in a variety of bacterial infections the mechanisms by which this cytokine mediates both protection and damage ca
โฆ LIBER โฆ
Immune mechanisms in bacterial and parasitic diseases: protective immunity versus pathology
โ Scribed by Georges E Grau; Robert L Modlin
- Book ID
- 103972743
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 965 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0952-7915
No coin nor oath required. For personal study only.
โฆ Synopsis
The immunological mechanisms that contribute to resistance versus susceptibility to bacterial and parasitic infection are central to the development of improved prophylactic and therapeutic strategies. The delineation of two subsets of CD4+ T cells in the mouse that regulate these responses has provided a tremendous advance in understanding disease pathogenesis. The elucidation of protective immune mechanisms distinct from those that cause tissue damage should lead to the development of appropriate vaccines against these devastating illnesses.
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