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Immune Enhancers Composed of Polyvalent Binding Sites of Anti-CD3 Antibodies

✍ Scribed by Wedrychowski, Andrzej ;Kim, Young-Woo ;Chang, Tse Wen


Book ID
109902911
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
815 KB
Volume
11
Category
Article
ISSN
1087-0156

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## Abstract CD30 is selectively expressed on the tumor cells of a variety of malignant disorders of the immune system and can therefore be used as a target for an anti‐CD30 antibody‐based immunotherapy. However, CD30 is cleaved at the cell surface by tumor necrosis factor‐α converting enzyme (TACE)