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Immune control in the absence of immunodominant epitopes: implications for immunotherapy of cytomegalovirus infection with antiviral CD8 T cells

✍ Scribed by Stefan Ebert, Niels A. W. Lemmermann, Doris Thomas, Angélique Renzaho, Matthias J. Reddehase, Rafaela Holtappels


Book ID
118785260
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
426 KB
Volume
201
Category
Article
ISSN
0300-8584

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## Abstract The dynamics of CMV pp65 and IE‐1‐specific IFNγ‐producing CD8^+^ (IFNγ CD8^+^) and CD4^+^ (IFNγ CD4^+^) T cells and CMV DNAemia were assessed in 19 pre‐emptively treated episodes of active CMV infection. Peripheral counts of IFNγ CD8^+^ and IFNγ CD4^+^ T cells inversely correlated with