Immortalized Testis Cell Lines From Estrogen Receptor (ER) α Knock-Out and Wild-Type Mice Expressing Functional ERα or ERβ

Estrogen receptor isoform-specific regul

Estrogen receptor isoform-specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERα or ERβ

✍ David G. Monroe; Barbara J. Getz; Steven A. Johnsen; B. Lawrence Riggs; Sundeep 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 172 KB

## Abstract Estrogen (17β‐estradiol, E2) plays pivotal roles in the function and maintenance of the skeleton, including the bone‐forming osteoblasts (OBs). The functions of E2 are largely mediated through two distinct estrogen receptor isoforms, ERα and ERβ, both of which are expressed in OBs. The